Micro-SIG: Comparative genomics, evolution, and regulation in microbes
Wednesday, February 28th, 2007
ISMB 2007 SIG Meeting
Date: Friday, July 20, 2007
Start time: 9:00 a.m. — End time: 6:30 p.m
Schedule
With more than 400 microbial genomes sequenced and more than 900 in the sequencing pipelines, comparative genomics is turning into a major tool for the annotation and analysis of sequences and genomes. To solve many problems related to the ever-growing number of bacterial sequences, new algorithms and software programs for post-sequencing functional analysis are being developed by the scientific community. Among them are whole genome comparison and visualization, discovery of coding regions and regulatory signals, and deducing the mechanisms and history of genome evolution has been a very active area of research in the last years.
Metagenomics, an emerging subdiscipline of microbiology, allows for the study of genomic sequences found in ecosystems, including genomes of species that are difficult to culture. They provide exciting opportunities to discover the extent of co-existing genetic diversity within natural ecosystems, and even microdiversity within populations of the same species.
This one-day SIG will be devoted to discussing the latest advances in computational techniques and biological insights in the area of comparative microbial genomics and regulation in bacteria. This session will bring together bioinformaticians and experimentalists, and will consist of invited talks and discussions chaired by leaders in the field. Talks will be grouped in four major areas:
- Comparative, population, and environmental genomics
- Elucidation of gene regulation in microbes
- Inference of genome phylogenies and dynamics
- Building and optimization of publicly available computational tools and databases for microbial analysis.
This session is organized by
Adam Arkin, Lawrence Berkeley National Laboratory and UC Berkeley
Eric Alm, MIT
Inna Dubchak, Lawrence Berkeley National Laboratory and Joint Genome Institute